Can exploiter disable localscript?

Explanation

Exploits are usually client sided, I highly doubt that exploiters could disable local scripts through some kind of heavy exploit but you should be fine as it will not affect the player but the exploiter itself. An example would be if an exploiter is using Btools for glitching through walls, other players would not see the affects of the exploiter as it will be client sided.

What you can do is make a script that will check the player's humanoid or character for anything sketchy, if it does then it will kick that certain player.

Solution

game.Players.PlayerAdded:Connect(function(player)
player.CharacterAdded:Connect(function(Character)
if player.Backpack:FindFirstChild("Btools") then -- You change Btools to the name of the exploit..
player:kick()

end
end)
end)

Solution 2

game.Players.PlayerAdded:Connect(function(player)
if player.Name == "ShedletSky" then -- Change ShedletSky to the name of the exploiter
player:kick()
end
end)

I hope this helps and please up vote this answer if it did so..