Any way to filter out chat for a keyboard command?

All you need to do in your code is check whether the TextBox for the chat is currently selected or not, and run your code accordingly. To accomplish this, we simply define a variable for the TextBox, and in the UserInputService event, do something like this:

local uis = game:GetService("UserInputService")

local player = game.Players.LocalPlayer

local chatBox = player.PlayerGui:WaitForChild("Chat"):FindFirstChild("ChatBar", true)

uis.InputBegan:connect(function(inputObject)
    if not chatBox:IsFocused() then
        print("This code prints this message!") --Your code here
    end
end)

I believe that this code should work for your purposes. If you have any further questions I am happy to answer them, just let me know. Hope this helps :)