Why is my GUI not clickable in play mode?

My GUI works/operates fine in studio mode but in play mode it is not working correctly. my GUI consists of a clickable screenGUI button that will bring up a much bigger GUI. In play mode, the first clickable screenGUI appears on my screen, however I am unable to click on it. I can click on it in STUDIO mode. Here is my code.

This script clones the "ScreenGUI" which is in ServerStorage to PlayerGUI in each player

game.Players.PlayerAdded:connect(function(plr)
game.ServerStorage.ScreenGui:clone().Parent = plr.PlayerGui 
end)

This is the code in my clickable screenGui that works in studio mode but not play mode (it is a LocalScript)

local imageButton = script.Parent
local menu = script.Parent.Parent.Frame
local close = script.Parent.Parent.TextButton
Open = false

imageButton.MouseButton1Click:connect(function()
    if Open == false then
    Open = true
    imageButton.Image = "rbxassetid://"
    wait(0.1)
    imageButton.Image = "rbxassetid://"
    imageButton.Visible = false
    menu.Visible = true
    close.Visible = true
    elseif Open == true then
    wait(0.2)
    Open = false    
    end
end)