Spawning A Block And An Explosion With It Failed?

If I read the discombobulated code correctly, this is the most likely setup of it.

function onTouch(hit)
    while true do
        local Wow = Instance.new("Part")
        Wow.Parent = game.Workspace
        Wow.Position = Vector3.new(-1609, 3473.895, -2417)
        Wow.CanCollide = false
        Wow.Locked = true
        Wow.BrickColor = BrickColor.new("New Yeller")
        Wow.Shape = ("Ball")
        wait(1)
        local Ex = Instance.new("Explosion")
        Ex.Parent = game.Workspace
        Ex.Position = Wow.Position
        Ex.BlastPressure = 5000000
        Ex.BlastRadius = 10
        Wow.Destroy()
        local M = Instance.new("Hint")
        M.Text = "SOMEONE HAS TOUCHED EPIC FACE'S BLOCK"
        wait(5)
        M.Destroy()
    end
end

script.parent.Touched:connect(onTouch)

Anyways from my limited experience with the only function I know by heart and soul (Touched) it appears that you're going for a direct "while true do"loop for whatever reason.

The function seems to be set out normal in regards to spawning in parts and such

    local Wow = Instance.new("Part")
        Wow.Parent = game.Workspace
        Wow.Position = Vector3.new(-1609, 3473.895, -2417)
        Wow.CanCollide = false
        Wow.Locked = true
        Wow.BrickColor = BrickColor.new("New Yeller")
        Wow.Shape = ("Ball")

Creating a Ball shaped part at Position (-1609, 3473.895, -2417) that is yellow, and non collidable and

    wait(1)
        local Ex = Instance.new("Explosion")
        Ex.Parent = game.Workspace
        Ex.Position = Wow.Position
        Ex.BlastPressure = 5000000
        Ex.BlastRadius = 10
        Wow.Destroy()
        local M = Instance.new("Hint")
        M.Text = "SOMEONE HAS TOUCHED EPIC FACE'S BLOCK"

A very powerful explosion set at the position of the newly formed "Wow" part that gives text and destroys the wow Part.

It does , however, seem that you've forgotten to call a part of the script that actually detects the player's presence.

Adding that in after the function which I'll localize I get

local function onTouch(hit)
    local explode = hit.Parent
    local humanoid = explode:FindFirstChild('Humanoid')
    if humanoid then
        local Wow = Instance.new("Part")
        Wow.Parent = game.Workspace
        Wow.Position = Vector3.new(-1609, 3473.895, -2417)
        Wow.CanCollide = false
        Wow.Locked = true
        Wow.BrickColor = BrickColor.new("New Yeller")
        Wow.Shape = ("Ball")
        wait(1)
        local Ex = Instance.new("Explosion")
        Ex.Parent = game.Workspace
        Ex.Position = Wow.Position
        Ex.BlastPressure = 5000000
        Ex.BlastRadius = 10
        Wow.Destroy()
        local M = Instance.new("Hint")
        M.Text = "SOMEONE HAS TOUCHED EPIC FACE'S BLOCK"
        wait(5)
        M.Destroy()
    end
end

script.Parent.Touched:connect(onTouch)

with the Humanoid detection occurring on lines 2-4

Now on the last line I get an error with parenting and the very fun likes, so for the sake of me personally being able to get past it, I'll bundle the whole thing into a neat little package in a variable called surpise

local surprise = script.Parent

local function onTouch(hit)
    local explode = hit.Parent
    local humanoid = explode:FindFirstChild('Humanoid')
    if humanoid then
        local Wow = Instance.new("Part")
        Wow.Parent = game.Workspace
        Wow.Position = Vector3.new(33, 0.5, -7) --This is the location of the part in my own testing world for the sake of my debugging. Just change it back to your original Vect3 when ready
        Wow.CanCollide = false
        Wow.Locked = true
        Wow.BrickColor = BrickColor.new("New Yeller")
        Wow.Shape = ("Ball")
        wait(1)
        local Ex = Instance.new("Explosion")
        Ex.Parent = game.Workspace
        Ex.Position = Wow.Position
        Ex.BlastPressure = 5000000
        Ex.BlastRadius = 10
        Wow:Destroy()
        local M = Instance.new("Hint")
        M.Text = "SOMEONE HAS TOUCHED EPIC FACE'S BLOCK"
        wait(5)
        M:Destroy()
    end
end

surprise.Touched:connect(onTouch)

Now when I touch it I get the yellow ball plopped on top of me that decimates me after a time. The only thing I didn't get was a "Hint" which I have no experience with, but it seems minor with your issue. The yellow ball, however keeps getting copied and copied and copied. So lets add a simple little debounce to the script.

local surprise = script.Parent
local canBoom = true
local cooldown = 7

local function onTouch(hit)
    local explode = hit.Parent
    local humanoid = explode:FindFirstChild('Humanoid')
    if humanoid and canBoom then
        canBoom = false
        local Wow = Instance.new("Part")
        Wow.Parent = game.Workspace
        Wow.Position = Vector3.new(33, 0.5, -7)
        Wow.CanCollide = false
        Wow.Locked = true
        Wow.BrickColor = BrickColor.new("New Yeller")
        Wow.Shape = ("Ball")
        wait(1)
        local Ex = Instance.new("Explosion")
        Ex.Parent = game.Workspace
        Ex.Position = Wow.Position
        Ex.BlastPressure = 5000000
        Ex.BlastRadius = 10
        Wow:Destroy()
        local M = Instance.new("Hint")
        M.Text = "SOMEONE HAS TOUCHED EPIC FACE'S BLOCK"
        wait(5)
        M:Destroy()
        wait(cooldown)
        canBoom = true
    end
end

surprise.Touched:connect(onTouch)

the function canBoom is required to be true for the inner script to fire, after the touch is detected it goes false to keep it from firing again, then at the end after a cooldown of whatever time you want (May probably not needed due to your wait right before, but meh whatever) it activates once more allowing the boom to happen. So now putting everything back to what I presume to apply to your world you get the final beautiful baby

local surprise = script.Parent
local canBoom = true
local cooldown = 7

local function onTouch(hit)
    local explode = hit.Parent
    local humanoid = explode:FindFirstChild('Humanoid')
    if humanoid and canBoom then
        canBoom = false
        local Wow = Instance.new("Part")
        Wow.Parent = game.Workspace
        Wow.Position = Vector3.new(-1609, 3473.895, -2417) --Put back to your coordinates
        Wow.CanCollide = false
        Wow.Locked = true
        Wow.BrickColor = BrickColor.new("New Yeller")
        Wow.Shape = ("Ball")
        wait(1)
        local Ex = Instance.new("Explosion")
        Ex.Parent = game.Workspace
        Ex.Position = Wow.Position
        Ex.BlastPressure = 5000000
        Ex.BlastRadius = 10
        Wow:Destroy()
        local M = Instance.new("Hint")
        M.Text = "SOMEONE HAS TOUCHED EPIC FACE'S BLOCK"
        wait(5)
        M:Destroy()
        wait(cooldown)
        canBoom = true
    end
end

surprise.Touched:connect(onTouch)

I hope this helps you a ton! As this was my first answer given, because I only have teachable experience with the touched function and all it's fun. Good luck with your game!

~MBacon15