BEST way to save data?

Just wondering, what would be the best method to save data with DataStoreService? I know how to use both SetAsync and UpdateAsync, but when should I use them? What would be better, a spawned loop that auto-saves data every few seconds or a PlayerRemoving event that saves it when the player leaves?

Here's my code for both cases:

Auto-save method:

local Datastore = game:GetService("DataStoreService"):GetDataStore("Example")
local Inc = Datastore:GetAsync("Test") or 0

spawn(function()
    while wait(5) do
        print("Autosaving...")
        Datastore:UpdateAsync("Test",function()
            return New
        end)
        print("Saved")
    end
end)

PlayerRemoving method:

local Players = game:GetService("Players")
local Datastore = game:GetService("DataStoreService"):GetDataStore("Example")
local Data = {}

Players.PlayerAdded:connect(function(Player)
    Data[Player.UserId] = Datastore:GetAsync("Test") or 0
    while wait(1) do
        Data[Player.UserId] = Data[Player.UserId] + 1
    end
end)

Player.PlayerRemoving:connect(function(Player)
    Datastore:UpdateAsync(Player.UserId,function()
        return Data[Player.UserId]
    end)
end)

Confusion

I feel like the PlayerRemoving one is a lot better, and more efficient, but there are also times when it won't save. Whereas the auto-save method seems to work fine, but over a period of time takes longer to save data and doesn't seem to efficient. Any help?