How i do make a script on a part that if you touch it that removes your tools?

I'll comment you through the code.

script.Parent.Touched:connect(function(Touch)

    local Player = game.Players:GetPlayerFromCharacter(Touch.Parent)--Using the Parameter that I named "Touched" to access the Player
    local Tool = Player.Character:GetChildren()--Gets all the Children that are Inside of the Character
    local BackPack = Player.Backpack:GetChildren()--Gets All the Children that Are Inside of Player's Backpack

for _,v in pairs (Tool) do --This in pairs loop loops through the Character Children
    if v:IsA("Tool") then--Check if any of the Children are ClassNamed "Tool".
    v.Parent = Player.Backpack--Parent the Tool to the Player's Backpack. The reason why I parented to the Player's Backpack instead of Destroying it is because when the Player holds the Tool and the tool is removed the Arm stays in the position as if it was still holding the tool.
    end end 

for _,v in pairs (BackPack) do--This in pairs loop loops through the Player's Backpack
    if  v:IsA("Tool") then--Check if there Any Object className "Tool" in the backpack
    v:Destroy()-- if it is then its Destroyed here.
    end end

end)

If you want a further explanation about on of the things I wrote please feel free to comment below! If I helped you solve/answer you problem please accept my answer.

Hmm. Well, in your question, the word 'while' has me confused. Do you want it to remove your tools when you touch the brick, and it never comes back? Or it comes back once you step off the brick? I'll set up both situations.

Never comes back:

script.Parent.Touched:connect(function(hit)
    if hit.Parent and game.Players:GetPlayerFromCharacter(hit.Parent) then
        local Player = game.Players:GetPlayerFromCharacter(hit.Parent) 
        for i,v in pairs(Player.Character:GetChildren()) do
            if v:IsA("Tool") or v:IsA("HopperBin") then
                v:Destroy()
            end
        end
        for i,v in pairs(Player.Backpack:GetChildren()) do
            if v:IsA("Tool") or v:IsA("HopperBin") then
                v:Destroy()
            end
        end
    end
end)

It comes back:

For this one, I recommend making a model Instance inside of the Player, to store all of the tools and HopperBins they had. Then, once they step off the brick, they get their tools back.

script.Parent.Touched:connect(function(hit)
    if hit.Parent and game.Players:GetPlayerFromCharacter(hit.Parent) and not game.Players:GetPlayerFromCharacter(hit.Parent):findFirstChild("Weapons") then
        local Player = game.Players:GetPlayerFromCharacter(hit.Parent)
        local Model = Instance.new("Model", Player)
        Model.Name = "Weapons"
        for i,v in pairs(Player.Character:GetChildren()) do
            if v:IsA("Tool") or v:IsA("HopperBin") then
                v.Parent =  Model
            end
        end
        for i,v in pairs(Player.Backpack:GetChildren()) do
            if v:IsA("Tool") or v:IsA("HopperBin") then
                v.Parent =  Model
            end
        end
    end
end)

script.Parent.TouchEnded:connect(function(unhit)
    if unhit.Parent and game.Players:GetPlayerFromCharacter(unhit.Parent) and game.Players:GetPlayerFromCharacter(unhit.Parent):findFirstChild("Weapons") then
        local Player = game.Players:GetPlayerFromCharacter(unhit.Parent)
        for i,v in pairs(Player.Weapons:GetChildren()) do
            v.Parent = Player.Backpack
        end
        Player.Weapons:Destroy()
    end
end)