Adjusting GUIs to screen resolution...?

To be honest, I've had enough with this-everyone tells me to use scale and I DO, but it still does not work. The game preview in studio has a smaller resolution, clearly, and when I put stuff to the edge in there, WITH SCALE, it's not on the edge when I open the game with the whole window taken up on my 1920x1080 resolution.

I just don't get it.