game.Players.HumanoidRootPart.Position.new = Vector3.new("-281.534, 44.658, -459.13")
Not too sure but maybe this is what you're looking for. Basically use math.random for each axis.
game.Players.HumanoidRootPart.Position.new = Vector3.new(math.random(0, -281.534), 44.658, math.random(0, -459.13))