How can i keep these loops continuing alongside eachother in this function?

Hello, My script checks if certain conditions are met in a menu so it clicks them but its not updating properly the loops dont keep going unless i trigger the function again. I am honestly lost and have been trying to figure this out for 2 days.~~~~~~~~~~~~~~~~~

    CompleteMission.MouseButton1Click:Connect(function()
    CompleteMissionOn = not CompleteMissionOn
    if CompleteMissionOn == true then
        CompleteMission.TextColor3 = Color3.fromRGB(11, 221, 101)
    else
        CompleteMission.TextColor3 = Color3.fromRGB(255, 255, 255)
    end 

    local function MineGemsOrGold(string)       
        if string == "GemOre5" and wait() and CompleteMissionOn == true then            
            game:GetService("ReplicatedStorage").GiveBonus:FireServer(5,5,2)            
        end             
        if string == "GoldOre8" and wait()  and CompleteMissionOn == true then              
            game:GetService("ReplicatedStorage").GiveBonus:FireServer(5,5,1)            
        end     
        for i, v in pairs(game:GetService("Workspace").Ores:GetChildren()) do           
            if v.CanCollide == true and v.name == string and CompleteMissionOn == true then                     
                fireclickdetector(v:FindFirstChildOfClass("ClickDetector"))                 
                wait()              
            end             
        end     
    end 

    while true and wait() do -- Main loop
        --gold and gems
        if MissionStats.Mission1.value == 4 or MissionStats.Mission2.value == 4 or MissionStats.Mission3.value == 4 then
            print("Gems = true")Gems = true
            print("Gold = false")Gold = false
        end
        while Gems == true and Gold == false and wait() do                      
            MineGemsOrGold("GemOre5")               
        end

        if  MissionStats.Mission1.value ~= 4 and MissionStats.Mission2.value ~= 4 and MissionStats.Mission3.value ~= 4 then
            print("Gems = false")Gems = false       
            print("Gold = true")Gold = true 
        end
        while Gold == true and Gems == false and wait() do
            MineGemsOrGold("GoldOre8")
        end         

        print(CompleteMissionOn)

        -- mission 1
        for i, v in pairs(MissionsToSkip) do

            if MissionsGui.Mission1.Mission.Text:find(v) and MissionStats.MissionCooldown1.Value == 0 then              
                print("waiting to skip")            
                game:GetService("ReplicatedStorage").ResetMission:FireServer(1)             
                print("M1 skipped")             
                wait()              
            elseif              
                MissionsGui.Mission1.Mission.Text:find("runes") then                
                print("M1 = rune mission")              
                while MissionStats.MissionProgress1.Value ~= MissionStats.MissionGoal1.Value do                 
                    game:GetService("ReplicatedStorage").BuyRune2:FireServer(1)                 
                    wait()                  
                end             
            elseif              
                MissionsGui.Mission1.Mission.Text:find("kryptonite") then               
                print("M1 = kryptonite mission")                                
                while MissionStats.MissionProgress1.Value ~= MissionStats.MissionGoal1.Value and CompleteMissionOn == true and wait() do                    
                    for i, v in pairs(game:GetService("Workspace").Ores:GetChildren()) do                       
                        if v.CanCollide == true and v.name == "KryptoniteOre4" and CompleteMissionOn == true then                           
                            fireclickdetector(v:FindFirstChildOfClass("ClickDetector"))                         
                            wait()                          
                        end                     
                    end                 
                end         
            elseif              
                MissionsGui.Mission1.Mission.Text:find("unobtainium") then          
                print("M1 = unobtainium mission")           
                while MissionStats.MissionProgress1.Value ~= MissionStats.MissionGoal1.Value and CompleteMissionOn == true and wait() do                    
                    for i, v in pairs(game:GetService("Workspace").Ores:GetChildren()) do                       
                        if v.CanCollide == true and v.name == "UnobtainiumOre4" and CompleteMissionOn == true then                          
                            fireclickdetector(v:FindFirstChildOfClass("ClickDetector"))                         
                            wait()                          
                        end                     
                    end                 
                end             
            elseif              
                MissionsGui.Mission1.Mission.Text:find("uranium") then              
                print("M1 = uranium mission")               
                while MissionStats.MissionProgress1.Value ~= MissionStats.MissionGoal1.Value and CompleteMissionOn == true and wait() do                    
                    for i, v in pairs(game:GetService("Workspace").Ores:GetChildren()) do                       
                        if v.CanCollide == true and v.name == "UraniumOre5" and CompleteMissionOn == true then                          
                            fireclickdetector(v:FindFirstChildOfClass("ClickDetector"))                         
                            wait()                          
                        end                     
                    end             
                end             
            elseif              
                MissionsGui.Mission1.Mission.Text:find("silver") then               
                print("M1 = silver mission")                
                while MissionStats.MissionProgress1.Value ~= MissionStats.MissionGoal1.Value and CompleteMissionOn == true and wait() do                    
                    for i, v in pairs(game:GetService("Workspace").Ores:GetChildren()) do                       
                        if v.CanCollide == true and v.name == "SilverOre8" and CompleteMissionOn == true then                           
                            fireclickdetector(v:FindFirstChildOfClass("ClickDetector"))                         
                        end                     
                    end                 
                end                 
            end                     
            if MissionStats.MissionProgress1.Value == MissionStats.MissionGoal1.Value then              
                game:GetService("ReplicatedStorage").ClaimMission:FireServer(1)             
                print ("M1 = claimed")              
            end         
        end
    end
end)~~~~~~~~~~~~~~~~~

the gems and gold part is supposed to update the minegemsorgold function to mine either gems or gold depending on the missions that appear but the main loop only fires once and doesnt update the string that gets sent to the function. Also all the other loops below dont work while the gold and gems loops are running.