The script won't detect the variable?

Have you tried putting the 2 variables at the top before the 'if' statement? Try that and see if it works.

script.Parent.MouseClick:Connect(function()

    local tweenService = game:GetService("TweenService") --Variable to the service.
    local Part1 = game.Workspace.PartDoor1 --Variable to a door.

    if script.Parent.Parent.BrickColor == BrickColor.new("Lime green") then

        script.Parent.Parent.BrickColor = BrickColor.new("Really red")

         local tweenInfo = TweenInfo.new(
             3,
             Enum.EasingStyle.Quad,
             Enum.EasingDirection,
             1, 
             true,
             2
            )
        end


    local Goals = {


        Position = Vector3.new(-49.346, 4.165, -117.723)

    }

    local tween = tweenService:Create(Part1, tweenInfo, Goals) --It won't detect Part1 and   
        tweenInfo.


    tween:Play()

end)