How do I make the GUI Disappear forever?

Hello, I made a Welcome GUI with a close button but if a character resets the GUI with the close button appear again is there any way I can make it Disappear even if the player dies?

You can destroy the gui e.g.

local Gui = game:GetService("StarterGui")

--//Whatever code you put
--//Now when you want to destroy it, write this code
Gui:Destroy()

I would use this put this as localscript inside the button that closes it

local event = game.ReplicatedStorage.RemoteEvent
script.Parent.MouseButton1Click:Connect(function()
      script.Parent.Parent.Visible = false
      event:FireServer()
end)

Put this in ServerScriptService as a script

local Name = game.StarterGui:FindFirstChild("GUINAME")
game.ReplicatedStorage.RemoteEvent.OnServerEvent:Connect(function()
      Name:Destroy()
end