Animation does not play when I have a weapon in hand?

I have an animation called "Anime" that moves the player's Right Arm. When I play the animation, it works fine. However, when I play it when a sword is equipped in the player's right hand, the animation does not play. No output or anything.

script.Parent.MouseButton1Click:connect(function()
	Anime = script.Parent.Anime
	Anim = game.Players.LocalPlayer.Character.Humanoid:LoadAnimation(Anime)
	Anim:Play()
end)

This is inside a GUI button inside a sword.

I'm totally baffled.

I think it has to deal with Lines 3 & 4.

script.Parent.MouseButton1Click:connect(function()
Anime = script.Parent.Anime
Anim = game.Players.LocalPlayer.Character.Humanoid:LoadAnimation(Anime) --Anim?
Anim:Play() --Anim?
end)