Region3 rotation for placement system?

My question: Rotating a Region3

I am making a placement system for a game and need collision. I am trying to use Region3s but when I rotate my model the region does not. I do not know if rotating Region3s is possible. Anyway here is my code for the Region3.NOTE: everything is inside of a LocalScript in a gui in StarterGui.

This is in the function that starts placement (Sets properties)

Code samples

regionPart1 = (model.PrimaryPart.Position - (model.PrimaryPart.Size / 2))
regionPart2 = (model.PrimaryPart.Position + (model.PrimaryPart.Size / 2))
	
while true do -- So it updates the region
	region = Region3.new(
		regionPart1, regionPart2
	)
			
	wait(0, 1)
end

Here is my collision detection code:

-- Detecting collision 

-- This is in the movement function so it gets called every time the mouse moves

regionPart1 = (model.PrimaryPart.Position - (model.PrimaryPart.Size / 2))	-- Update
regionPart2 = (model.PrimaryPart.Position + (model.PrimaryPart.Size / 2))

for i, v in pairs(modelInRegion) do
	if v.Parent:FindFirstChild("Primary") ~= nil then
		ModelsFound[v.Parent.Primary.Name] = v.Parent.Primary
		isColliding = true
	else
		isColliding = false
	end
end
		
for index, value in pairs(ModelsFound) do
	spawn(function()
		isColliding = true
	end)
end

Failed solution

I have tried updating the CFrame of the region when the model rotates like this:

region.CFrame = CFrame.new(regionPart1, regionPart2) * CFrame.Angles(0, math.rad(Rot), 0)

In the output it said CFrame could not be set.

End

If there is anyway to rotate a Region3 by 90 degrees then let me know (Not asking for a whole script just either the place to find the answer or a explanation of how it works)! Thanks for helping!

(Also if there is a better way to detect collision then that would also be helpful)