how do I make my sell home gui button script work on filtering enabled?

This is a NORMAL script inside the gui button

function onButtonClicked()
local x = game.Workspace:FindFirstChild("Home"..script.Parent.Parent.Parent.Parent.Name)
if not (x) then
return
else
x.Home:Remove()
x.Name = "Home"
wait(.5)
s = game.Lighting["Home"..script.Parent.Parent.Parent.Parent.Name]
s.Parent = x
s.Name = "Home"
end
end
script.Parent.MouseButton1Click:connect(onButtonClicked)

When scripting with Guis, you should use a localscript. For FilteringEnabled Client-to-Server communication (basically, a player's computer sending a message to the server), you should use RemoteEvents. I'll show you an example. Lets say you have a RemoteEvent in game.ReplicatedStorage. This example has a button that, when clicked, adds a part to the workspace.

-- LocalScript
-- The Parent is a TextButton, parented a ScreenGui that is parented to the PlayerGui.

local Button = script.Parent
local Remote = game.ReplicatedStorage:WaitForChild('RemoteEvent')

Button.MouseButton1Click:Connect(function()
  Remote:FireServer()
end)

-- Script
-- The Parent i game.ServerScriptService

local Remote = game.ReplicatedStorage:WaitForChild('RemoteEvent')

Remote.OnServerEvent:Connect(function(Player)
  local Part = Instance.new('Part', workspace)
  print(Player.Name .. ' added a part to the workspace!')
end)

When doing something that ALL players should see, use a server script (aka a Script). When doing something that only ONE player should see, use a local script. LocalScripts should be in a Player's PlayerScripts, PlayerGui, a Tool, or a Player's Character. Hope this helped..