I have this but I am pretty sure this is wrong. I think I need something like Udim2 or something along those lines but I dont know what it is .
if game:GetService("UserInputService").ModalEnabled == false then
script.Parent.Position=(0.454, 0),(0.442, 75)
end

3 comments
http://wiki.roblox.com/index.php?title=API:Class/GuiObject/Position
.Position=UDim2.new(xscale,xoffset,yscale,yoffset) is the correct format
Did you get my hint @lukeb50?