Can you do a MouseButton1Down function on an invisible screen? Click for more!

I have a few questions about MouseButton1Down. I'm basically trying to make a click anywhere on the screen to continue thing.

Here's the list;

Can you do MouseButton1Down on a frame?

Can you use MouseButton1Down on a TextLabel?

Would MouseButton1Down Fire if I clicked an invisible button? Visible = false

Would MouseButton1Down Fire if I clicked a transparent button? Transparency = 0.9,1etc.

Can I use MouseButton1Down on the screen it self?

Please answer these questions. Thanks for any answer.

1: No 2: No 3: No 4: Yes 5: Not that I know of so no.