How would I 'disconnect' a spawn?

Yes.

Let me write an example that we can work off of because you didn't

spawn(function()
	while wait() do
		print(math.random())
	end
end)

There are multiple ways we can end this.

• #1, using break

You can end loops by using the break function. Example,

spawn(function()
	while wait() do
		local num = math.random()
		print(num)
		if num == 0.5 then--Very unlikely
			break
		end
	end
end)

• #2, using return

You can use return in any function to "end" it.

spawn(function()
	while wait() do
		local num = math.random()
		print(num)
		if num == 0.5 then--Very unlikely
			return
		end
	end
end)

I'm "pretty sure" you can do this

Ending function remotely,

You a variable that can be changed elsewhere in the script and if the variable equals "true" end the function.

local RunningLoop = false

spawn(function()
	RunningLoop = true
	while wait() do
		print(math.random())
		if RunningLoop == false then
			break
		end
	end
end)

game.Workspace.Part.Touched:connect(function(p)
	if p.Name = "ball" then
		RunningLoop = true
	end
end)

The touched event is an example of turning off the loop with a function/event.

If you need something explained further please ask.

Good Luck!

If I helped, please don't forget to accept my answer.