This page, on Region3's, confuses me before the third sentence. It shows the following code. Pay special attention to the comment.
Region3.new( Vector3.new(1, 1, 1), Vector3.new(9, 9, 9) )
-- a Region3 with a size of (8, 8, 8) and a position at (5, 5, 5)
Why would it have a size of 888 and a position at 555? Shouldn't it be 111 and 999? This makes no sense, and the wiki doesn't explain.
More info on Region3 itself would also be greatly appreciated, as I didn't find that article very well written or clear.

1 comment
The Vector3s in the first line define the corners. So a box with a corner at 1, 1, 1 and another corner at 9, 9, 9 would have each side be 8 and halfway between would be at 5 on all axes.