It's not making the number of the GUi go up

local Player = script.Parent.Parent
local mouse = Player:GetMouse()

function Dig()
   if mouse.Target.Name == "Nope" then
	script.Parent.Disabled = true
end
	if mouse.Target ~= nil then
		if mouse.Target.Name == "Dirt" then
		mouse.Target.Transparency = mouse.Target.Transparency +1
		if mouse.Target.Transparency > 0.9 then
			mouse.Target:remove()
			script.Parent.Parent.PlayerGui.ScreenGui.Frame.Dirt.Value.Value = script.Parent.Parent.PlayerGui.ScreenGui.Frame.Dirt.Value.Value +1
		end
		end
		
		if mouse.Target.Name == "Silver" then
		mouse.Target.Transparency = mouse.Target.Transparency +0.5
		if mouse.Target.Transparency > 0.9 then
			mouse.Target:remove()
			script.Parent.Parent.PlayerGui.ScreenGui.Frame.Silver.Value.Value = script.Parent.Parent.PlayerGui.ScreenGui.Frame.Silver.Value.Value +1
		end
		end
			
		if mouse.Target.Name == "Diamond" then
		mouse.Target.Transparency = mouse.Target.Transparency +0.3
		if mouse.Target.Transparency > 0.9 then
			mouse.Target:remove()
			script.Parent.Parent.PlayerGui.ScreenGui.Frame.Diamond.Value.Value = script.Parent.Parent.PlayerGui.ScreenGui.Frame.Diamond.Value.Value +1
		end
		end
			
		if mouse.Target.Name == "Ruby" then
		mouse.Target.Transparency = mouse.Target.Transparency +0.2
		if mouse.Target.Transparency > 0.9 then
			mouse.Target:remove()
			script.Parent.Parent.PlayerGui.ScreenGui.Frame.Ruby.Value.Value = script.Parent.Parent.PlayerGui.ScreenGui.Frame.Ruby.Value.Value +1
		end
		end
			
		if mouse.Target.Name == "Emerald" then
		mouse.Target.Transparency = mouse.Target.Transparency +0.16
		if mouse.Target.Transparency > 0.9 then
			mouse.Target:remove()
			script.Parent.Parent.PlayerGui.ScreenGui.Frame.Emerald.Value.Value = script.Parent.Parent.PlayerGui.ScreenGui.Frame.Emerald.Value.Value +1
		end
		end
			
		if mouse.Target.Name == "Gold" then
		mouse.Target.Transparency = mouse.Target.Transparency +0.01
		if mouse.Target.Transparency > 0.9 then
			mouse.Target:remove()
			script.Parent.Parent.PlayerGui.ScreenGui.Frame.Gold.Value.Value = script.Parent.Parent.PlayerGui.ScreenGui.Frame.Gold.Value.Value +1
		end
		end
			
		end

end

mouse.Button1Down:connect(Dig)

First: tab your code correctly.

Issue:

• You check if mouse.Target is not nil after using it (line 5)

• You use script.Parent.Parent over and over even though you have Player defined to be the same thing

After fixing those, have a massive amount of code reuse. For instance, just mouse.Target appears 32 times.

Simple fix: let hover = mouse.Target.

Let's get rid of the "Nope" case. It doesn't make sense to disable scripts -- that's dangerous. It also doesn't fit in with the rest of what's going on.

function Dig()
	local hover = mouse.Target
	if hover then -- Not nil
		if hover.Name == "Dirt" then
			hover.Transparency = hover.Transparency +1
			if hover.Transparency > 0.9 then
				hover:remove()
				Player.PlayerGui.ScreenGui.Frame.Dirt.Value.Value = Player.PlayerGui.ScreenGui.Frame.Dirt.Value.Value +1
			end
		end
	....

Now we are repeatedly looking at hover.Name. Let's use kind and also use elseifs.

function Dig()
	local hover = mouse.Target
	if hover then -- Not nil
		local kind = hover.Name
		if kind == "Dirt" then
			hover.Transparency = hover.Transparency +1
			if hover.Transparency > 0.9 then
				hover:remove()
				Player.PlayerGui.ScreenGui.Frame.Dirt.Value.Value = Player.PlayerGui.ScreenGui.Frame.Dirt.Value.Value +1
			end
		elseif kind == "Silver" then
			hover.Transparency = hover.Transparency +0.5
			if hover.Transparency > 0.9 then
				hover:remove()
				Player.PlayerGui.ScreenGui.Frame.Silver.Value.Value = Player.PlayerGui.ScreenGui.Frame.Silver.Value.Value +1
			end
	....

Now there is still a massive amount of reuse.

This chunk appears over and over:

hover.Transparency = hover.Transparency + AAA
if hover.Transparency > 0.9 then
	hover:Remove()
	Player.PlayerGui.ScreenGui.Frame.BBB.Value.Value = Player.Parent.PlayerGui.ScreenGui.Frame.BBB.Value.Value +1
end

The only difference is that AAA depends on the kind of material, and BBB is the name of hover.

Let's use that, and instead of repeating ourselves, use the same code to do this:

function Dig()
	local hover = mouse.Target
	if hover then -- Not nil
		local kind = hover.Name
		local rates = {
			Dirt = 1,
			Silver = 0.5,
			Diamond = 0.3,
			Ruby = 0.2,
			Emerald = 0.16,
			Gold = 0.01
		}
		local rate = rates[kind]
		if rate then
			-- It is a kind of block we can mine
			hover.Transparency = hover.Transparency + rate
			if hover.Transparency > 0.9 then
				hover:Remove()
				Player.PlayerGui.ScreenGui.Frame[kind].Value.Value = Player.PlayerGui.ScreenGui.Frame[kind].Value.Value + 1
			end
		end
	end
end

We should probably just have a reference to the inventory = Player.PlayerGui.ScreenGui.Frame to avoid that extra long line (and let us move it later, if need be)

local Player = script.Parent.Parent
local mouse = Player:GetMouse()
local inventory = Player.PlayerGui.ScreenGui.Frame
				....
				inventory[kind].Value.Value = inventory[kind].Value.Value + 1
				....

Now that we have reasonable code....

What does it do instead? Is there an error? Have you tried anything at all to figure out what's wrong yourself?

Are you sure there is a Value object called Value inside of, e.g., inventory.Dirt? Are you sure that Dirt isn't just the Vlaue object?