How can I make a local script enable/disable another local script?

Sadly, you cannot re-run the script once you re-enabled it. Instead, put the script inside the "enable/disable" script and make that script a function/thread.

For example: you have script 1 and 2. Script 1 prints "hi" in the Output every second, meanwhile Script 2 enables/disables Script 1 in order to play and stop the loop multiple times. Here's the thing: it doesn't work like that. You have to make Script 1 a function/thread inside Script 2 then run it.

Before:

--Script 1
while task.wait(1) do
	print("hi") --prints hi every 1 second
end

--Script 2
local Script1 = workspace.Script1

while task.wait(5) do
	Script1.Enabled = not Script1.Enabled --toggles Script1.Enabled true/false every 5 second
end

After:

--Script 2

local Script1 = coroutine.create(function() --creates a function/thread copy of Script 1
	while task.wait(1) do
		print("hi")
	end
end)

coroutine.resume(Script1) -- "enables" it
while task.wait(5) do
	local status = coroutine.status(Script1) -- gets its status as a string
	
	if status == "running" then -- if Script1 is "enabled"
		coroutine.close(Script1) -- this sets the thread status to dead or "disabled"
	elseif status == "dead" then -- if Script1 is "disabled"
		Script1 = coroutine.create(function() -- creates a new one
			while task.wait(1) do
				print("hi")
			end
		end)
		
		coroutine.resume(Script1) -- "re-enables" it
	end
end

Note: This is just an example. Don't copy-and-paste it directly to your script or it will error. Do this method on your own.

Hope this helped!

Learn more about coroutines