How Do I Get A Brick To Face A Player Using Cframes?

you cant do Target_To_Face.Position because you are getting the children but not their characters, on top of that you will need to loop

while true do
local Part_To_Face = game.Workspace.Part
local Target_To_Face = game.Players:GetChildren()
	local closest = Vector3.new(0,0,0)
	for _, v in pairs(Target_To_Face) do
		if v.Character then
			if closest == nil then closest = v.Character.HumanoidRootPart.Position Part_To_Face.CFrame = CFrame.new(Part_To_Face.Position, closest) end

			if (v.Character.HumanoidRootPart.Position - Part_To_Face.Position).Magnitude < (closest-Part_To_Face.Position).Magnitude then closest = v.Character.HumanoidRootPart.Position Part_To_Face.CFrame = CFrame.new(Part_To_Face.Position, closest) end
		end
	end
    wait(0.01)
end

Basically what this does is, it loops through all the players and finds their humanoidrootpart, the closest one is what the part will face at.

Tell me if it works, click accept if it does!